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TREATMENT LAG at Medical Glossary

What is it? The time required, or presumed to be required, for a treatment to exert its full effect.

Medical Definition Added By: Brianna

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Medicine Term Clinical trial is A clinical trial is a scientific study involving patient care designed to assess the value of a new treatment or therapy compared to current practice. Clinical trials can be either Phase 1, 2, 3, or 4. Phase 1 clinical trials are the earliest type of investigation and are used to determine the appropriate amount of therapy (e.g. drug, radiation etc) to give to a patient,; what the side effects are and if the therapy is active against their cancer. Phase 1 trials usually involve a small number of patients, usually around 20 or so. Phase 2 clinical trials: If a therapy gives promising results in Phase 1 trials, then the therapy is given to a greater number of patients either all having the same type of cancer, of different types of cancer to gather more accurate data on how well the therapy works compared with current therapy. Usually there are many more patients in a Phase 2 trial, but this can vary. Phase 3 clinical trails are large trials usually involving thousands of patients. This is because reliable information is needed to show subtle differences on many patients compared to standard therapy. Each patient is different, so is is only by averaging results from many patients that the true effectiveness can be shown. Phase 4 clinical trials are conducted to determine the long term safety and effectiveness of therapies that have been approved for use in cancer. For more information please see our web page on Clinical Trials under Cancer Research